Selected Publications (Journals)
Refereed and peer-reviewed journal articles
Ankush Aggarwal, Alison M. Pouch, Eric Lai, John Lesicko, Paul A. Yushkevich, Joseph H. Gorman III, Robert C. Gorman, and Michael S. Sacks. In-vivo heterogeneous functional and residual strains in human aortic valve leaflets. Journal of Biomechanics, 2016 [link]
Joao S. Soares, Kristen R. Feaver, Will Zhang, David Kamensky, Ankush Aggrawal, Michael S. Sacks, Biomechanical behavior of heterograft biomaterials for bioprosthetic heart valves: characterization, simulation, and performance. Cardiovascular Engineering and Technology, (in press) [link]
Ankush Aggarwal and Michael S. Sacks. An inverse modeling approach for semilunar heart valve leaflet mechanics: exploitation of tissue structure. Biomechanics and Modeling in Mechanobiology, 15(4): 909-932, 2016 [link]
& . An advanced computational bioheat transfer model for a human body with an embedded systemic circulation. Biomechanics and Modeling in Mechnobiology, 2015 [link]
& . Synergy Between Intercellular Communication and Intracellular Ca2+ Handling in Arrhythmogenesis. Annals of Biomedical Engineering, 2015 [link]
& . A benchmark study of numerical schemes for one-dimensional arterial blood flow modelling. International Journal for Numerical Methods in Biomedical Engineering, 2015 [link]
David Kamensky, Ming-Chen Hsu, Dominik Schillinger, John A. Evans, Ankush Aggarwal, Yuri Bazilevs, Michael S. Sacks, Thomas J. R. Hughes. An immersogeometric variational framework for fluid--structure interaction: Application to bioprosthetic heart valves. Computer Methods in Applied Mechanics and Engineering, Vol 284(0): 1005-1053, 2015 [link]
Chung-Hao Lee, Rouzbeh Amini, Yusuke Sakamoto, Christopher Carruthers, Ankush Aggarwal, Robert C. Gorman III, Joseph H. Gorman, and Michael S. Sacks. Mitral valves - a computational framework. In Multiscale Modeling in Biomechanics and Mechanobiology, pages 223-255. Springer London, 2015 [link]
Ankush Aggarwal and Michael S. Sacks. A framework for determination of heart valve’s mechanical properties using inverse-modeling approach. Functional Imaging and Modeling of the Heart, volume 9126 of Lecture Notes in Computer Science, pages 285-294, 2015 [link]
Ankush Aggarwal, Giovanni Ferrari, Erinn M Joyce, Michael J. Daniels, Rachana Sainger, Joseph H. Gorman III, Robert Gorman, Michael S. Sacks. Architectural trends in the human normal and bicuspid aortic valve leaflet and its relevance to valve disease, Annals of Biomedical Engineering, Vol 42(5): 986-998, 2014 [link]
Ankush Aggarwal, Vanessa S. Aguilar, Chung-Hao Lee, Giovanni Ferrari, Joseph H. Gorman, Robert C. Gorman, and Michael S. Sacks. Patient-specific modeling of heart valves: From image to simulation. Functional Imaging and Modeling of the Heart, volume 7945 of Lecture Notes in Computer Science, pages 141-149, 2013 [link]
R.L.T Bevan, P. Nithiarasu, R van Loon, I Sazonov, Parallel Explicit and Quasi-Implicit CBS procedures for modelling blood flow within healthy and diseased carotid arteries. Journal of Biomechanics , in preparation.
I.Sazonov and P. Nithiarasu, Semi-automatic surface and volume mesh generation for subject-specific biomedical geometries, Int. J. Num. Meth. in Biomedical Engineering, 28, 133-157, 2012.
R. L.T. Bevan, I.Sazonov, P.H. Saksono, P.Nithiarasu, R. van Loon, H. Luckraz and S.Ashraf, Patient-specific blood flow simulation through an aneurismal thoracic aorta with a folded proximal neck, International Journal For Numerical Methods In Biomedical Engineering 27, 1167–1184, 2011, DOI:10.1002/cnm.1425.
K. Chitra, S. Vengadesan, T. Sundararajan and P. Nithiarasu, Non-Newtonian blood flow study in a model cavo-pulmonary vascular system, Int. J. Num. Meth. Fluids, 66, 269-283, 2011.
A.J. Gil, A. Arranz Carreño, J. Bonet and O. Hassan, The Immersed Structural Potential Method for haemodynamic applications, Journal of Computational Physics, Volume 229, Issue 22, 2011, pages 8613-8641, DOI: 10.1016/j.jcp.2010.08.005.
P. Nithiarasu, R. Bevan, I. Sazonov, R. van Loon, H. Luckraz, M. Collins, A. Garnham Influences of domain extensions to a moderately stenosed patient-specific carotid bifurcation: Investigation of wall quantities, International Journal of Numerical Methods for Heat & Fluid Flow, 21(8), 952—979, 2011, DOI: 10.1108/0961553111117774.
P.H. Saksono, P. Nithiarasu and I. Sazonov, Computational flow studies in a subject-specific human upper airway using a one-equation turbulence model. Influence of nasal cavity, International Journal for Numerical Methods in Engineering, 87, 96-114, 2011.
I.Sazonov, S.Y. Yeo, R.L.T. Bevan, P. Nithiarasu, R. van Loon and X. Xie, A robust subject-specific modelling pipeline for arterial blood flow dynamics – A review, International Journal for Numerical Methods in Biomedical Engineering, 27(8), 1167-1184 2011, DOI: 10.1002/cnm.1425.
R.L.T. Bevan, P. Nithiarasu, R. van Loon, I. Sazonov, H.Luckraz, A. Garnham, Application of a locally conservative Galerkin (LCG) method for modelling blood flow through a patient-specific carotid bifurcation, Int. J. Num. Meth. Fluids, 64, 1274-1295, 2010, DOI: 10.1002/fld.2313.
C.T. Bowles, S. New, R. van Loon, S.A. Dreger, G. Biglino, C. Chan, K.H. Parker, A.H. Chester, M.H. Yacoub, P.M. Taylor, Hydrodynamic evaluation of a bioreactor for tissue engineering heart valves, Cardiovasc. Eng. & Technol., 2010, DOI: 10.1007/s13239-010-0007-5.
R. van Loon, Towards computational modelling of aortic aortic stenosis, Int. J. Num. Meth. Biomed. Engng, 26, 405-420, 2010.
K. Chitra, S. Vengadesan, T. Sundararajan and P. Nithiarasu, An investigation of pulsatile flow in a model cavo-pulmonary vascular system, Communications in Numerical Methods in Engineering with biomedical applications, 25, 1061-1083, 2009.
I. Sazonov, P.H. Saksono, P. Nithiarasu, R. van Loon, H. Luckraz, S. Ashraf, Patient-specific blood flow simulation through an aneurismal thoracic aorta with a folded neck, Int. J. Num. Meth. Biomed. Eng., 2009.
J. Mynard and P. Nithiarasu, A 1D arterial blood flow model incorporating ventricular pressure, aortic valve and regional coronary flow using the locally conservative Galerkin (LCG) method, Communications in Numerical Methods in Engineering, 24, 367-417, 2008.
J. Mynard and P. Nithiarasu, Development of a New One-Dimensional Model of the Systemic Circulation Incorporating Ventricular Pressure, Aortic Valve and Coronary Flow, Heart, Lung and Circulation, 17S, S237-S238, 2008.
P. Nithiarasu, O. Hassan, K. Morgan, N.P. Weatherill, P. Ebden, H. Whittet and C. Fielder, Steady flow through a realistic human upper airway geometry, International Journal for Numerical Methods in Fluids, 57, 631-651, 2008.
C. Wood, A.J. Gil, O. Hassan and J. Bonet, A partitioned coupling approach for dynamic fluid-structure interaction with applications to biological membranes, International Journal for Numerical Methods in Fluids, Volume 57, 2008, pages 555-581, DOI: 10.1002/d.1815.
P. Nithiarasu, C-B. Liu and N. Massarotti, Laminar and turbulent flow through a model human upper airway using unstructured meshes, Communications in Numerical Methods in Engineering, 23, 1057-1069, 2007.
R. van Loon, P.D. Anderson, F.N. van de Vosse, A model suitable for heart valve dynamics combining fluid-structure interaction and rigid-solid contact, J. Comp. Phys., 217, 806-823, 2006.
R. van Loon, P.D. Anderson, F.P.T. Baaijens, F.N. van de Vosse, A three-dimensional fluid-structure interaction model for heart valve modelling, C.R. Mecanique, 333, 856-866, 2005.
R. van Loon, P.D. Anderson, J. de Hart, F.P.T. Baaijens, A combined fictitious domain/adaptive meshing method for fluid-structure interaction in heart valves, Int. J. Num. Meth. Fluids, 533-544, 2004.